【摘 要】目的了解前S1蛋白(PreS1)、乙型肝炎病毒(HBVDNA)及丙氨酸氨基转移酶(ALT)与急性乙型肝炎(AHB)病程的关系。方法 采用酶联免疫吸附试验(ELISA)、核酸扩增(PCR)荧光定量检测技术和双试剂法分别检测PreS1抗原、HBVDNA和ALT。结果 不同病程AHB患者血清PreS1抗原与ALT阳性符合率较高(P>0.05)，HBVDNA与ALT相比阳性符合率较低(P<0.01)。结论 AHB患者治疗过程中，PreS1抗原与ALT阴转基本一致，先于HBVDNA阴转，提示疾病的转归及预后较好。

    【关键词】 PreS1；HBVDNA；乙型肝炎病毒

    Dynanlic obervations between Pres1,HBV DNA and ALT in AHBDAI Hong-bin,ZHU Wei.The Funing people′s Hospital, Jiangsu Province,Funing 224400,China

    【Abstract】 Objective To find out the relation between PreS1、HBVDNA and ALT and the course of the disease of AHB.Methods By ELISA，PCR，fluorescent light quantitative technology and double reagent PreS1、HBVDNA and ALT were checked.Results For different courses of the disease of AHB ......